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Publikationen 2001

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Der zuerst aufgeführte Mitarbeiter aus der Klinik und Poliklinik für Innere Medizin I ist hervorgehoben.

Bielecka-Kowal O, Distler O, Neidhart M, Künzler P, Rethage J, Nawrath M, Carossino A, Pap T, Müller-Ladner U, Michel BA, Sierakowski S, Matucci-Cerinic M, Gay RE, Gay S. Evidence of 5-lipoxygenase overexpression in the skin of patients with systemic sclerosis. Arthritis Rheum 2001; 44: 1865-1875.

Cousin SP, Hügl S R, Wrede C, Kajio H, Myers M G Jnr, Rhodes C J. Free fatty acid-induced inhibition of glucose and insulin-like growth factor I-induced deoxyribonucleic acid synthesis in the pancreatic beta-cell line INS-1. Endocrinology 2001; 142: 229-240.

Dickson LM, Lingohr MK, McCuaig J, Hügl SR, Snow L, Kahn BB, Myers MG, Rhodes CJ. Differential activation of protein kinase B and p70S6K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). J Biol Chem 2001; 276: 21110-21120.

Distler O, Pap T, Kowal-Bielecka O, Meyringer R, Guiducci S, Landthaler M, Schölmerich J, Michel BA, Gay RE, Matucci-Cerinic M, Gay S, Müller-Ladner U. Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: Role of platelet derived growth factor and effects on monocyte chemotaxis and collagen synthesis. Arthritis Rheum 2001; 44: 2665-2677.

Endlicher E, Knüchel R, Hauser T, Szeimies R-M, Schölmerich J, Messmann H. Endoscopic fluorescence detection of low and high grade dysplasia in Barrett’s esophagus using systemic or local 5-aminolaevulinic acid sensitization. GUT 2001; 48: 314-319.

Fleck M, Zhang H-G, Kern ER, Mountz, JD. Treatment of chronic sialadenitis in a murine model of Sjögren’s syndrome by local Fas ligand gene-transfer. Arthritis Rheum 2001; 44: 964-973.

Grossmann J, Artinger M, Grasso AW, Kung H-J, Schölmerich J, Fiocchi, C, Levine AD. Hierarchical cleavage of focal adhesion kinase (FAK) by caspases alters FAK-mediated signal transduction during apoptosis of normal human intestinal epithelial cells. Gastroenterology 2001; 120: 79-88.

Guba M, Cernaianu G, Koehl G, Geissler EK, Jauch K-W, Anthuber M, Falk W, Steinbauer M. A primary tumor promotes dormancy of solitary tumor cells before inhibiting angiogenesis. Cancer Res 2001; 61: 5575-5579.

Härle P, Noisakran S, Carr DJ. The application of a plasmid DNA encoding IFN-1 postinfection enhances cumulative survival of herpes simplex virus type 2 vaginally infected mice. J Immunology 2001; 166: 1803-1812.

Hsu HC, Zhang HG, Song GG, Xie J, Liu D, Yang PA, Fleck M, Wintersberger W, Zhou, T, Edwards CK III, Mountz JD. Fas ligand producing antigen presenting cell gene therapy ameliorates arthritis induced by M. pulmonis in B6 gld/gld mice. Arthritis Rheum 2001; 44: 2146-2159.

Kowal-Bielecka O, Distler O, Neidhart M, Künzler P, Rethage J, Nawrath M, Carossino A, Pap T, Müller-Ladner U, Michel BA, Sierakowski S, Matucci-Cerinic M, Gay RE, Gay S. Evidence for 5-lipoxygenase overexpression in the skin of patients with systemic sclerosis: A newly identified pathway to skin inflammation in systemic sclerosis. Arthritis Rheum 2001; 44: 1865-1875.

Liang JS, Distler O, Cooper DA, Jamil H, Deckelbaum RJ, Ginsberg HN, Sturley SL. HIV protease inhibitors protect apolipoprotein B from degradation by the proteasome: a potential mechanism for protease inhibitor-induced hyperlipidemia. Nat Med 2001; 7: 1327-1331.

Martin-Villalba A, Hahne M, Kleber S, Vogel J, Falk W, Schenkel J, Krammer PH. Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke. Cell Death Differentiation 2001; 8: 679-686.

Nakajima A, Seroogy CM, Sandora MR, Tarner IH, Costa GL, Taylor-Edwards C, Bachmann MH, Contag CH, Fathman CG. Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis. J Clin Invest 2001; 107:1293-1301.

Schnabl B, Bradham CA, Bennett BL, Manning AM, Stefanovic B, Brenner DA. TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells. Hepatology 2001; 34: 953-963.

Schnabl B, Kweon YO, Frederick JP, Wang XF, Rippe RA, Brenner DA. The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology 2002; 34: 89-100.

Schwabe RF, Schnabl B, Kweon YO, Brenner DA. CD40 activates NF-kappaB and c-Jun N-terminal kinase and enhances chemokine secretion of activated human hepatic stellate cells. J Immunol 2001; 166: 6812-6819.

Schwarzenbeck D, Reng CM. The worst days of my life. Lancet 2001 (Suppl.); 358: S44. IF 15.397

Seitz C, Müller P, Krieg R, Männel DN, Hehlgans T. Identification of an intracellular expressed p75 TNF receptor isoform mediating NF-kappa-B activation and protection from TNF-induced cytotoxicity. J Biol Chem 2001; 276: 19380-19395.

Seufert J, Ebert K, Müller J, Eulert J, Hendrich C, Werner E, Schütze N, Schulz G, Kenn W, Richtmann H, Palitzsch K-D, Jakob F. Octreotide therapy for tumor-induced osteomalacia. New Engl J Med 2001; 354: 1883-1888.

Stingele K, Haas J, Zimmermann T, Stingele R, Hübsch-Müller C, Freitag M, Storch-Hagenlocher B, Hartmann M, Wildemann B. Independent HIV replication in paired CSF and blood viral isolates during antiretroviral therapy. Neurology 2001; 56: 355-361.

Straub RH, Cutolo M. Involvement of the hypothalamic-pituitary-adrenal/gondal axis and the peripheral nervous system in rheumatoid arthritis. Arthritis Rheum 2001; 44: 493-507.

Strauch UG, Mueller RC, Li XY, Cernadas M, Higgins JM, Binion DG, Parker CM. Integrin alpha E(CD103)beta 7 mediates adhesion to intestinal microvascular endothelial cell lines via an E-cadherin-independent interaction. J Immunol 2001; 166: 3506-3514.

Tarner I, Fathman GC. Gene therapy in autoimmune disease. Curr Opin Immunol 2001; 13: 676-682.

Uesugi T, Froh M, Arteel GE, Bradford BU, Thurman RG. Toll-like receptor 4 is involved in the mechanism of early alcohol-induced liver injury in mice. Hepatology 2001; 34: 101-108.

Uesugi T, Froh M, Arteel GE, Bradford BU, Gäbele E, Wheeler MD, Thurman RG. Delivery of lB superrepressor gene with adenovirus reduces early alcohol-induced liver injury in rats. Hepatology 2001; 34: 1149-1157

Van Cutsem E, Twelves C, Cassidy J, Allman D, Bajetta E, Boyer M, Bugat R, Findlay M, Frings S, McKendrick J, Osterwalder B, Perez-Manga G, Rosso R, Rougier P, Schmiegel WH, Seitz JF, Thompson P, Vieitez JM, Weitzel C, Harper P. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study. J Clin Oncol 2001; 19: 4097-4106.

Wheeler MD, Kono H, Yin M, Rusyn I, Froh M, Connor HD, Mason RP, Samulski RJ, Thurman RG. Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats. Gastroenterology 2001; 120: 1241-1250.

Wiest R, Ming-Hung T, Groszmann RJ. Octreotide potentiates PKC-dependent vasoconstrictors in portal-hypertensive and control rats. Gastroenterology 2001; 120: 975-983.

Yin M, Bradford BU, Wheeler MD, Uesugi T, Froh M, Goyert SM Thurman RG. Reduced early alcohol-induced liver injury in CD14-deficient mice. J Immunol 2001; 166: 4737-4742.

Yin M, Gäbele E, Wheeler MD, Connor H, Bradford BU,Dikaova A, Rusyn I, Mason R, Thurman RG. Alcohol-induced free radicals: direct toxicants of signaling molecules? Hepatology 2001; 34: 935-942.

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