Publikationsliste Prof. Dr. Strauß

2010

Evolution and functional divergence of the anoctamin family of membrane proteins. Milenkovic VM, Brockmann M, Stöhr H, Weber BH, Strauss O. BMC Evol Biol. 2010 Oct 21;10:319 [Full paper PDF]
Effect of bestrophin-1 on L-type Ca2+ channel activity depends on the Ca2+ channel beta-subunit. Reichhart N, Milenkovic VM, Halsband CA, Cordeiro S, Strauss O. Exp Eye Res. 2010 Nov;91(5):630-9 [Full paper PDF]
Expression of Orai genes and I(CRAC) activation in the human retinal pigment epithelium. Cordeiro S, Strauss O. Graefes Arch Clin Exp Ophthalmol. 2010 Jul 6 [Full paper PDF]
PKC{alpha} is essential for the proper activation and termination of rod bipolar cell response. Ruether K, Feigenspan A, Pirngruber J, Leitges M, Baehr W, Strauss O. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):6051-8. Epub 2010 Jun 16 [Full paper PDF]
Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion. Cordeiro S, Seyler S, Stindl J, Milenkovic VM, Strauss O. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):6001-8. Epub 2010 Jun 10 [Full paper PDF]
Regulation of the renin expression in the retinal pigment epithelium by systemic stimuli. Milenkovic VM, Brockmann M, Meyer C, Desch M, Schweda F, Kurtz A, Todorov V, Strauss O. Am J Physiol Renal Physiol. 2010 Aug;299(2):F396-403. Epub 2010 Jun 2 [Full paper PDF]
The presence of bestrophin-1 modulates the Ca2+ recruitment from Ca2+ stores in the ER. Neussert R, Müller C, Milenkovic VM, Strauss O. Pflugers Arch. 2010 Jun;460(1):163-75. Epub 2010 Apr 22 [Full paper PDF]

2009

Gawad AE, Schlichting L, Strauss O, Zeitz O (2009) Antiapoptotic properties of erythropoietin: novel strategies for protection of retinal pigment epithelial cells. Eye (Lond). 23(12):2245-50 [Abstract] [Full paper HTML] [Full paper PDF]
Stöhr H, Heisig JB, Benz PM, Schöberl S, Milenkovic VM, Strauss O, Aartsen WM, Wijnholds J, Weber BH, Schulz HL (2009) TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. J Neurosci. 29(21):6809-18 [Abstract] [Full paper HTML] [Full paper PDF]
Strauss O (2009) The role of retinal pigment epithelium in visual functions. Ophthalmologe. 106(4):299-304. Review. German [Abstract] [Full paper HTML] [Full paper PDF]
Strauss O (2009) Retinal pigment epithelium. Ophthalmologe. 106(4):297-8. German. No abstract available [Full paper HTML] [Full paper PDF]
Zeitz O, Berna-Thill M, Bartsch U, Strauss O, Richard G (2009) Oxidative stress at the retinal pigment epithelium - experimental implications for protection. Klin Monbl Augenheilkd. 226(1):27-30. Review. German [Abstract] [Full paper HTML] [Full paper PDF]

2008

Wimmers S, Halsband C, Seyler S, Milenkovic V, Strauss O (2008). Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells. Mol Vis. 2008; 14:2340-8 [Abstract] [Full paper HTML] [Full paper PDF]
Karl MO, Kroeger W, Wimmers S, Milenkovic VM, Valtink M, Engelmann K, Strauss O (2008) Endogenous Gas6 and Ca²⁺ -channel activation modulate phagocytosis by retinal pigment epithelium. Cell Signal. 20(6): 1159-1168 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Wimmers S, Coeppicus L, Rosenthal R, Strauss O (2008) Expression profile of voltage-dependent Ca²⁺ channel subunits in the human retinal pigment epithelium. Graefes Arch Clin Exp Ophthalmol. 246(5): 685-692 [PubMed abstract] [Full paper HTML] [Full paper PDF]

2007

Wimmers S, Strauss O (2007) Basal Calcium Entry in Retinal Pigment Epithelial Cells Is Mediated by TRPC Channels. Invest Ophthalmol Vis Sci. 48(12): 5767-5772 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Lopes VS, Ramalho JS, Owen DM, Karl MO, Strauss O, Futter CE, Seabra MC (2007) The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epithelium. Traffic 8(5): 486-499 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Rosenthal R, Heimann H, Agostini H, Martin G, Hansen LL, Strauss O (2007) Ca²⁺ channels in retinal pigment epithelial cells regulate VEGF secretion rates in health and disease. Mol. Vision 13: 443-456 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Wesolowski R, Sommer A, Arndt HD, Koert U, Reiss P, Wimmers S, Strauss O (2007) Functional studies of synthetic gramicidin hybrid ion channels in CHO cells. Chembiochem. 8(5): 513-520 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Wimmers S, Karl MO, Strauss O (2007) Ion channels in the RPE. Prog Retin Eye Res. 26(3): 263-301 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Zeitz O, Schlichting L, Richard G, Strauss O (2007) Lack of antioxidative properties of vitamin C and pyruvate in cultured retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol. 245(2): 276-281 [PubMed abstract] [Full paper HTML] [Full paper PDF]

2006

Marmorstein LY, Wu J, McLaughlin P, Yocom J, Karl MO, Neussert R, Wimmers S, Stanton JB, Gregg RG, Strauss O, Peachey NS, Marmorstein AD (2006) The light peak of the electroretinogram is dependent on voltage-gated calcium channels and antagonized by bestrophin (best-1). J Gen Physiol. 127(5): 577-589 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Wollmann G, Lenzner S, Berger W, Rosenthal R, Karl MO, Strauss O (2006) Voltage-dependent ion channels in the mouse RPE: Comparison with Norrie disease mice. Vision Res. 46(5): 688-698 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Rosenthal R, Bakall B, Peachey N, Wimmers S, Wadelius C, Marmorstein A, Strauss O (2006) Expression of bestrophin-1, the product of the VMD2 gene, modulates voltage-dependent Ca²⁺ channels in retinal pigment epithelial cells. FASEB J. 20(1): 178-180 [PubMed abstract] [Full paper HTML] [Full paper PDF]

2005

Mergler S, Strauss O, Strowski M, Prada J, Drost A, Langrehr J, Neuhaus P, Wiedenmann B, Ploeckinger U (2005) Insulin-like growth factor-1 increases intracellular calcium concentration in human primary neuroendocrine pancreatic tumor cells and a pancreatic neuroendocrine tumor cell line (BON-1) via R-type Ca²⁺ channels and regulates chromogranin a secretion in BON-1 cells. Neuroendocrinology 82(2): 87-102 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Rosenthal R, Malek G, Salomon N, Peill-Meininghaus M, Coeppicus L, Wohlleben H, Wimmers S, Bowes Rickman C, Strauss O (2005) The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells. Biochem. Biophys. Res. Commun. 337(1): 241-247 [PubMed abstract] [Full paper, HTML] [Full paper, PDF]
Thieme H, Steinhausen K, Ottlecz A, Lambrou GN, Strauss O, Wiederholt M, Rosenthal R (2005) Effects of unoprostone and endothelin-1 on L-type channel currents in human trabecular meshwork cells. Ophthalm. Res. 37(6): 293-300 [PubMed Abstract] [Full paper, PDF]
Strauss O (2005) The retinal pigment epithelium in visual function. Physiol Rev. 85(3): 845-881 [PubMed abstract] [Full paper HTML] [Full paper PDF]
Strauss O (2005) Morbus Best Ophthalmologe 102(2): 109-110 [Full paper HTML] [Full paper PDF]
Strauss O, Rosenthal R (2005) Funktion des Bestrophins. Ophthalmologe 102(2): 122-126 [PubMed abstract] [Full paper HTML] [Full paper PDF]

2004

Rosenthal R, Wohlleben H, Malek G, Schlichting L, Thieme H, Bowes Rickman C, Strauss O (2004) Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration. Biochem. Biophys. Res. Comm. 323(4): 1203-1208 [PubMed abstract] [Full paper HTML] [Full paper PDF]

2002 - 2003

Fidzinski P, Knoll A, Rosenthal R, Schrey A, Vescovi A, Koert U, Wiederholt M, Strauß O (2003) Electrophysiological response of cultured trabecular meshwork cells to synthetic ion channels. Chem. Biol. 10(1): 35-43 [PubMed abstract] [Full paper]
Rosenthal R, Strauss O (2003) Investigations of RPE cells of choriodal neovascular membranes from patients with age-related macula degeneration. Adv. Exp. Med. Biol. 533: 107-113 [PubMed reference]
Rosenthal R, Strauss O (2002) Ca²⁺ channels in the RPE. Adv. Exp. Med. Biol. 514: 225-235 [PubMed reference]
Strauss O, Rosenthal R, Dey D, Beninde J, Wollmann G, Thieme H, Wiederholt M (2002) Effects of protein kinase C on delayed rectifier K(+) channel regulation by tyrosine kinase in rat retinal pigment epithelial cells. Invest. Ophthalmol. Vis. Sci. 43(5): 1645-1654 [PubMed abstract] [Full text PDF]
Mergler S, Strauss O (2002) Stimulation of L-type Ca²⁺channels by increase of intracellular InsP3 in rat retinal pigment epithelial cells. Exp. Eye. Res. 74(1): 29-40 [PubMed abstract] [Full text PDF]

2001

Thieme H, Hildebrand J, Choritz L, Strauss O, Wiederholt M (2001) Muscarinic receptors of the M2 subtype in human and bovine trabecular meshwork. Graefe's Arch. Clin. Exp. Ophthalmol. 239(4): 310-315 [PubMed abstract] [Full text PDF]
Rosenthal R, Thieme H, Strauss O (2001) Fibroblast growth factor receptor 2 (FGFR2) in brain neurons and retinal pigment epithelial cells act via stimulation of neuroendocrine L-type channels (Ca(v)1.3). FASEB J. 15(6): 970-977 [PubMed abstract] [Full paper]
Stumpff F, Boxberger M, Thieme H, Strauss O, Wiederholt M (2001) Flufenamic acid enhances current through maxi-K channels in the trabecular meshwork of the eye. Curr. Eye Res. 22(6): 427-437 [PubMed abstract] [Full paper PDF]

2000

Thieme H, Nuskovski M, Nass JU, Pleyer U, Strauss O, Wiederholt M (2000) Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A. Invest. Ophthalmol. Vis. Sci. 41(13): 4240-4246 [PubMed abstract] [Full text HTML]
Strauss O, Buss F, Rosenthal R, Fischer D, Mergler S, Stumpff F, Thieme H (2000) Activation of neuroendocrine L-type channels (a1D subunits) in retinal pigment epithelial cells and brain neurons by pp60c-src. Biochem. Biophys. Res. Comm. 270(3): 806-810 [PubMed abstract]
Steinhausen K, Stumpff F, Strauss O, Thieme H, Wiederholt M (2000) Influence of muscarinic agonists and tyrosine kinase inhibitors on L-type Ca²⁺channels in bovine and human trabecular meshwork cells. Exp. Eye Res. 70(3): 285-293 [PubMed abstract] [Full text PDF]

1999

Valtink M, Engelmann K, Strauss O, Krüger R, Loliger C, Ventura AS, Richard G (1999) Physiological features of primary cultures and subcultures of human retinal pigment epithelial cells before and after cryopreservation for cell transplantation. Graefes Arch. Clin. Exp. Ophthalmol. 237(12): 1001-1006 [PubMed abstract]
Thieme H, Nass JU, Nuskovski M, Bechrakis NE, Stumpff F, Strauß O, Wiederholt M (1999) The effects of Protein Kinase C (PKC) on Trabecular Meshwork and Ciliary Muscle Contractility. Invest. Ophthalmol. Vis. Sci. 40(13): 3254-3261 [PubMed abstract]
Strauß O, Steinhausen K, Mergler S, Stumpff F, Wiederholt M (1999) Involvement of protein tyrosine kinase in the InsP3-induced activation of Ca²⁺-dependent Cl^- currents in cultured cells of the rat retinal pigment epithelium. J. Membr. Biol. 169(3): 141-153 [PubMed abstract]
Stumpff F, Que Y, Boxberger M, Strauß O, Wiederholt M (1999) Stimulation of maxi-K channels in trabecular meshwork by tyrosine kinase inhibitors. Invest. Ophthalmol. Vis. Sci. 40(7): 1404-1417 [PubMed abstract]

1998

Strauß O, Stumpff F, Mergler S, Wienrich M, Wiederholt M (1998) The Royal College of Surgeons rat: an animal model for inherited retinal degeneration with a still unknown genetic defect. Acta Anat. (Basel) 162(2-3): 101-111 [PubMed abstract]
Mergler S, Steinhausen K, Wiederholt M, Strauß O (1998) Altered regulation of L-type channels by protein kinase C and protein tyrosine kinases as a pathophysiologic effect in retinal degeneration. FASEB J. 12(12): 1125-1134 [PubMed abstract]
Strauß O, Steinhausen K, Wienrich M, Wiederholt M (1998) Activation of a Cl^--conductance by protein kinase-dependent phosphorylation in cultured rat retinal pigment epithelial cells. Exp. Eye Res. 66(1): 35-42 [PubMed abstract]
Wiederholt M, Groth J, Strauß O (1998) Role of protein tyrosine kinase on regulation of trabecular meshwork and ciliary muscle contractility. Invest. Ophthalmol. Vis. Sci. 39(6): 1012-1020 [PubMed abstract]

1997

Strauß O, Mergler S, Wiederholt M (1997) Regulation of L-type calcium channels by protein tyrosine kinase (PTK) and protein kinase C (PKC) in cultured rat and human retinal pigment epithelial cells. FASEB J. 11(11): 859-867 [PubMed abstract]
Stumpff F, Strauß O, Boxberger M, Wiederholt M (1997) Characterization of maxi-K-channels in trabecular meshwork and their regulation by cGMP. Invest. Ophthalmol. Vis. Sci. 38(9): 1883-1892 [PubMed abstract]

1995 - 1996

Strauß O, Wiederholt M, Wienrich M (1996) Activation of Cl^- currents in cultured rat retinal pigment epithelial cells by intracellular applications of inositol-1,4,5-triphosphate: differences between rats with retinal dystrophy (RCS) and normal rats. J. Membr. Biol. 151(2): 189-200 [PubMed abstract]
Noske W, Strauß O, Levarlet B, Wiederholt M, Hirsch M (1995) Incomplete belts of tight junctions in cultured non-pigmented human ciliary epithelial cells. J. Submicrosc. Cytol. Pathol. 27(1): 1-8 [PubMed abstract]

1994

Strauß O, Weiser T, Wienrich M (1994) Potassium currents in cultured cells of the rat retinal pigment epithelium. Comp. Biochem. Physiol. A 109(4): 975-983 [PubMed abstract]
Strauß O, Wienrich M (1994) Extracellular matrix proteins as substrate modulate the pattern of calcium channel expression in cultured rat retinal pigment epithelial cells. Pflügers Arch. 429(1): 137-139 [PubMed abstract]
Strauß O, Wienrich M (1994) Ca²⁺-conductances in cultured rat retinal pigment epithelial cells. J. Cell Physiol. 160(1): 89-96 [PubMed abstract]

1991 - 1993

Strauß O, Wienrich M (1993) Cultured retinal pigment epithelial cells from RCS rats express an increased calcium conductance compared with cells from non-dystrophic rats. Pflügers Arch. 425(1-2): 68-76 [PubMed abstract]
Strauß O, Richard G, Wienrich M (1993) Voltage-dependent potassium currents in cultured human retinal pigment epithelial cells. Biochem. Biophys. Res. Commun. 191(3): 775-781 [PubMed abstract]
Strauß O, Stahl F, Wiederholt M (1992) Elevation of cytosolic free calcium in cultured ciliary epithelial cells by histamine: effects of verapamil and staurosporine. J. Ocul. Pharmacol. 8(4): 359-366 [PubMed abstract]
Strauß O, Graszynski K (1992) Isolation of plasma membrane vesicles from the gill epithelium of the crayfish, Orconectes limosus Rafininesque, and properties of the Na⁺/H⁺-exchanger. Comp. Biochem. Physiol. A 102: 519-526.
Strauß O, Wiederholt M (1991) Transepithelial resistance of ciliary epithelial cells in culture: Functional modification by protamine and extracellular calcium. Comp. Biochem. Physiol. A 100(4): 987-993 [PubMed abstract]

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